Treatment options for hepatitis D (HDV)
Patients with severe chronic hepatitis D (HDV) can be treated with pegylated interferon. Interferon is a substance that stimulates the immune system. However, this treatment is only effective in about 30% of those affected.
Bulevirtide is a specific drug therapy for hepatitis D (HDV). It prevents HDV and HBV from entering liver cells and can be given in combination with pegylated interferon. This treatment is effective in 53% of those affected.
Liver transplantation may be necessary in patients with liver cirrhosis or acute fulminant hepatitis D (HDV).
Important stages from diagnosis to therapy
It is difficult to distinguish the symptoms of acute viral hepatitis D from another form of acute hepatitis.
If you have not been vaccinated against hepatitis B (HBV) and are at risk of contracting HBV or HDV , see your doctor for clarification and guidance. If you knowingly become acutely infected with hepatitis B (HBV), there is the possibility of post-exposure prophylaxis, which must be initiated within forty-eight hours
To find out whether you have contracted HBV or HDV, your blood will be tested in a laboratory.
If a HBV infection is confirmed, testing for hepatitis delta (HDV) should then take place immediately. Additionally, you should receive a referral to a liver specialist (hepato-gastroenterologist).
A hepatologist is a medicalspecialists for liver disease who will examine you in the hospital or in a doctor's office.
A HDV test should generally be performed in patients infected with HBV. More liver-specific tests can be done in the hospital.
Based on the results of the additional tests, your hepatologist, supported by a multidisciplinary medical team, will recommend and prescribe an appropriate HBV/HDV treatment.
Depending on the type of treatment prescribed, you will receive this directly at the hospital or you can obtain the medication from a pharmacy.
It is important to take your medication as directed and to read the patient information leaflets carefully.
Your hepatologist will monitor your treatment to check its effectiveness, as well as monitor the progression of the disease to detect any complications or signs of worsening.
Be assured that you are not alone on this journey or in dealing with this disease. It is very important to have someone to talk to. This can be a friend or family member. A patient organisation can also be a helpful contact point.